The arrival of COVID vaccines have stirred excitement and optimism for a swift end to the global pandemic, with some seeing the shot as a 91Ƶfree pass91Ƶ to soon gather and socialize as they did pre-2020.
Not so fast, experts say.
Canada91Ƶs first phase of vaccine rollout 91Ƶ targeting front-line health-care workers, long-term care residents and staff, and some Indigenous populations 91Ƶ began last month and is expected to stretch into March before the inoculation process is opened to a broader population this spring.
While experts agree the end of the pandemic is in sight, they say it will take time to determine what level of protection the new vaccines actually provide 91Ƶ and whether they prevent us from spreading the virus.
Experts expect mask mandates, limits on gatherings, and physical distancing measures to continue even as more of us get vaccinated, at least through part of 2021.
91ƵUntil we get to a level of herd immunity where we have around 70 per cent of our population vaccinated worldwide, there91Ƶs going to be that question of transmission,91Ƶ said Jason Kindrachuk, a virologist with the University of Manitoba. 91ƵAnd that91Ƶs certainly a concern for us.91Ƶ
Both Pfizer-BioNTech and Moderna, the two vaccines currently approved for use in Canada, were shown in clinical trials to have a 95 per cent efficacy in preventing severe infection from the virus that causes COVID-19. And while Moderna has some evidence suggesting it also decreases transmission, more data is needed.
Some vaccines, like the one for HPV, offer complete protection from infection and transmission, while others like the flu shot primarily work against acquiring the virus and lessening the severity of symptoms. Kindrachuk says part of the reason for that is the way our immune systems respond to different vaccines.
The COVID vaccine seems to effectively produce neutralizing antibodies, he says, 91Ƶbut not necessarily enough to stop the virus from potentially getting into some of our cells.91Ƶ
Dr. Sumon Chakrabarti, an infectious disease physician in Mississauga, Ont., says answers to the transmission question will only come as 91Ƶlarge swathes of the population91Ƶ start getting vaccinated worldwide.
We may see that the inoculations do decrease transmission, he says, and restrictions could be lifted earlier than experts expect.
91ƵBut as it stands in January 2021, when you get vaccinated you91Ƶll want to still act like you were doing before: physical distancing, keeping contacts low, masking indoors,91Ƶ Chakrabarti said. 91ƵAs the pandemic starts to ease up, things will change.91Ƶ
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Being able to still transmit the virus becomes less of a problem as more and more people are vaccinated, experts say.
But Horacio Bach, an adjunct professor of infectious diseases at UBC, doesn91Ƶt expect SARS-CoV-2 to ever be eradicated.
If 30 per cent of the population isn91Ƶt immunized, the virus will continue to circulate through them, he says. So effective treatment for COVID-19 will be needed to deal with lingering cases.
91ƵViruses don91Ƶt have brains but they91Ƶre not stupid,91Ƶ he said. 91ƵThey will continue to find hosts.91Ƶ
Dr. Isaac Bogoch, an infectious disease expert with the University of Toronto, says COVID-1991Ƶs potential staying power will have less of an impact once pressure is relieved on the health-care system. And that will be achieved by vaccinating high-risk populations early in the rollout.
The first indication that vaccines are working will be a reduction in deaths as long-term care and other high-risk groups are immunized, he says, while case counts will be the last to decrease. That means infection prevention controls will need to be followed while community transmission is still happening.
91ƵEventually you91Ƶll start to see a reduction in cases as these vaccine programs roll up, and then we91Ƶll start to see public health measures slowly lifted as the year progresses, post-April,91Ƶ he said. 91ƵWe91Ƶll probably see a gradual shift allowing larger outdoor gatherings, then indoor gatherings, and eventually lifting of mask mandates.91Ƶ
An exact timeline for reaching that level is hard to predict, however.
While a highly effective vaccine will allow us to reach herd immunity quicker, Bogoch says a 95 per cent efficacy in a clinical trial might not actually translate that successfully in the real world.
Since efficacy was based on a two-dose regime, Bogoch expects that number to drop if people don91Ƶt return for a second shot. It91Ƶs also still unknown how effective the vaccine is for segments of the population excluded from clinical trials.
So visiting a grandparent or other high-risk individual in the next couple months will be risky, Bogoch says, even if they91Ƶve been vaccinated.
91ƵThe effectiveness is probably going to be lower (than the trials showed),91Ƶ he said. 91ƵAnd we91Ƶll need to see how this plays out in real time to help drive our behaviours.91Ƶ
This report by The Canadian Press was first published Jan. 8, 2020.
Melissa Couto Zuber, The Canadian Press